ARTHOKNEE PLUS  40 mg / 2ml

Arthroknee Plus  40 mg / 2ml

High molecular weight 1.5-1.9 Mw (Mda). – LONG-TERM EFFECTIVE

Arthroknee Plus

  • Provides joint lubricity
  • Protects the cartilage, increases its durability
  • Supports the joints
  • Increases the load bearing capacity of the joints
  • Pain decreases in joints with increased lubricity
  • Increases mobility and flexibility
  • Reduces trauma

Arthroknee Plus  40 mg / 2ml

Arthroknee Plus is a transparent, sterile, non-pyrogenic and viscoelastic solution supplied in a 2 ml syringe.

Arthroknee Plus acts as a substitute of synovial fluid into joints affected by degenerative or mechanical osteoarthritis that gives pain or reduced mobility.

Arthroknee Plus acts only in the joint into which it is injected, without exercising any systemic action.


Main ingredient: hyaluronic acid sodium salt 2%. Other ingredients: sodium chloride, sodium phosphate and water for injectable preparations (to volume).


Hyaluronic acid is an natural polysaccharide present in numerous human tissues, especially synovial fluid, and acts on joints both as a cartilage and ligament lubricant and as a shock absorber. Many studies have shown that the injection of hyaluronic acid into joints affected by osteoarthritis restores synovial fluid viscosity and elasticity, with a consequent reduction in pain and improvement in the joint’s mobility.


Hyaluronic acid is a substance found naturally in joint cartilage. Provides the lubricity of the knee joint fluid and has a protective effect on cartilage cells. In gonarthrosis (knee osteoarthritis)  the level of intra-articular hyaluronic acid decreases, the nourishment and lubricity of the joint decreases, and the load-bearing capacity of the joint decreases.


Osteoarthritis is joint inflammation. It is characterized by deterioration, wear and tear of joint cartilages. Osteoarthritis, which is a degenerative joint disease, is known as arthritis among the people. It is the most common joint disease in people over the age of 50. Osteoarthritis can affect any joint in the body. The joints most commonly affected are knees, hips, hands, feet, fingers and spine. In osteoarthritis, a deterioration occurs in the articular cartilage structure. As a result of this, joint destruction starts and causes swelling, limitation of movements and pain in the joint. Osteoarthritis is 3 times more common in women.


There are some risk factors that increase the risk of developing osteoarthritis.


Wear and abrasion (mechanical factors): Repetitive minor traumas over the years, excessive physical activity disrupts the load-bearing ability of the joint and causes cartilage destruction. Excess weight (obesity) causes excessive load on joints.

Hereditary predisposition: The substances in the cartilage content are now known to be hereditary.

Age: osteoarthritis is a disease of middle and old age. With aging, changes occur in the articular cartilage and consequently its endurance decreases. Therefore, as the age progresses, the incidence of osteoarthritis increases. Women are more likely to develop osteoarthritis.

Other diseases affecting bones and joints and surgical interventions: Diseases such as gout, rheumatoid arthritis, diabetic neuropathy, paget’s disease, septic arthritis and congenital hip dislocation increase the risk of developing osteoarthritis. Surgical interventions experienced in the past also increase the risk.

Made in: Italy